LRRK2 and Parkinson disease: The presence of multiple minor variants (p.S16478, p.R1628P, and p.G2385R) in the LRRK2 gene is usually correlated with a lower age at the Parkinson ́s disease onset—52.6 (±12.3) years—as compared to patients without these risk variants—62.5 years (±10.5) [52].