Another potential phenomenon that may occur in this group of patients is the increased serum neutralization capacity of TNF-α, which leads to a decrease in the activity of TNF-alpha in the area of the nerve tissue and, as a result, a lack of activation of remyelination [83], for which the appropriate concentration of TNF-alpha is required (such an effect was discovered in patients with multiple sclerosis) [115]. The gene discussed is TNF; the disease is multiple sclerosis.