NPM1 and myeloid neoplasm: Other genes commonly mutated in myeloid neoplasms, such as FLT3 (fms like tyrosine kinase 3), DNMT3A (DNA Methyltransferase 3 Alpha), IDH1/2 (Isocitrate Dehydrogenase (NADP(+)) 1/2), NPM1 (Nucleophosmin 1), and RUNX1, are rare and almost mutually exclusive [7].