ATM and breast carcinoma: K.J. Jerzak et al., in detail discussed different data about radiation therapy outcome in the case of different types of ATM pathology: it was found that some data suggest an increase in toxicity, other data suggest, radiation-induced clinical benefit; some studies propose that ATM mutations might increase the risk of breast cancer after RT, others say that ATM status should not be used to make treatment decisions with respect to radiotherapy [25].