LYST and Chediak-Higashi syndrome: Additionally, mutations in the HPS, CHS/LYST, MC1R, and OA1 genes have also been reported to cause different types of OCA through Hermansky-Pudlak syndrome (MIM# 203300), red-haired OCA2 (MIM#203200), Chediak–Higashi syndrome (MIM# 214500), and X-linked ocular albinism (MIM#300500), respectively [12,13,14,15,16].