Analysis of the transcriptome from the brain of living patients with PD consistently showed dysregulated PD biomarkers between the brain and blood compared to HCs; the downregulated genes were ANKRD22, IL1R2, MARCH1, and OLFML2B, while the upregulated genes were BTNL9 and STOX1 [116]. Here, STOX1 is linked to Parkinson disease.