So far, there are no data for such a combined screening approach, but it is well-known that cTnI is an appropriate biomarker of primary cardiac involvement in IRD [48,49,50], and cardiac MRI is able to detect myocardial inflammation, subendocardial vasculitis, and fibrosis in early and established IRD, even in the absence of echocardiogram abnormalities [51,52,53,54]. The gene discussed is TNNI3; the disease is vasculitis.