CXCL8 and COVID-19: The extracted risk factors for ICU admission and/or mortality were combined with the APACHE-II score, which has been reported in [34,35] as one of the most contributory variables for the risk prediction of COVID-19, to develop an ICU scoring index with accuracy 0.9 based on IL-6, IL-8, IL-1b and TNF and thus quantify the severity of the disease.