For example, markers of myeloid lymphatic endothelial cell progenitors (M-LECPs) were found to be expressed on a portion of lymphatic vessels in breast cancer tissue, but not in normal breast tissue, and M-LECPs co-expressed high levels of PROX1, LYVE-1, podoplanin, and VEGFR-3 [36]. This evidence concerns the gene LYVE1 and breast cancer.