ANGPT2 and juvenile dermatomyositis: For a small subset of untreated JDM patients (n = 11), serum neopterin level correlated strongly with CXCL10 (IP-10) (R2 = 0.88 p < 0.0001), as well as other biomarkers, CXCL11 (I-TAC) (R2 = 0.85 p < 0.0001), and to a lesser degree, angiopoietin 2 (R2 = 0.37 p = 0.038) (Figure 3).