Subjects with low LDL-C and high ApoB (group 2) also had the highest insulin and glucose levels compared to those with high LDL-C and high ApoB, including fasting blood glucose (FBG) (117.5 ± 6.0 and 112.7 ± 3.2 mg/dL, respectively), insulin (16.6 ± 1.4 and 13.1 ± 1.0 μU/mL, respectively) and homeostatic model assessment of insulin resistance (HOMA-IR) (5.3 ± 0.9 and 3.7 ± 0.3, respectively) (all p < 0.001, Table 1). The gene discussed is INS; the disease is Insulin resistance.