CD8A and hypertensive disorder: In the study conducted to determine the T lymphocyte phenotype in newly diagnosed hypertensive patients, Youn et al. [26] showed a significantly higher number of circulating immunosenescent pro-inflammatory CD8+ T lymphocytes in 71 individuals with hypertension aged 51.6 ± 11.2 years when compared to 71 healthy ones aged 51.5 ± 12.2 years.