INS and type 1 diabetes mellitus: The FreeStyle Libre flash glucose monitoring system was proven in the IMPACT and REPLACE studies [2,3] to reduce time in hypoglycemia below 70 mg/dL by 38% (IMPACT) and 43% (REPLACE) over 26 weeks, for adults with type 1 (T1D) or type 2 diabetes (T2D) on insulin, compared with the finger-prick method for the self-monitoring of blood glucose (SMBG).