On the other hand, anti-inflammatory cytokines interleukin-13 (IL-13), interleukin-4 (IL-4), interleukin-10 (IL-10) and transforming growth factor-β (TGF-β) appear on the fourth day after infection and ameliorate the exacerbation of inflammation and participate in the healing of lesions [41]. The gene discussed is IL4; the disease is infection.