In addition, a recent Raman study of human breast cancer cell lines (MDA-MB-231, MDA-MB-435s and SK-BR-3) [38] also detected a noticeable lipid expression in the MDA-MB-231 TNBC cells when compared to the non-TNBC (luminal HER2+) SK-BR-3, which was suggested to be due to an increased content in unsaturated fatty acids (mostly within the membrane). This evidence concerns the gene ERBB2 and breast cancer.