MAP1LC3A and acute myeloid leukemia: Supplementary Figure S1A–C shows that both mCherry and GFP fluorescence increased in each AML cell line treated for 24 h by increasing doses of PIK-III or SAR-405. This inhibition was both confirmed by the detection of mCherry and GFP fluorescence by microscopy, as shown in Supplementary Figure S1D, and the autophagy markers p62, Beclin and LC3 by Western blotting in Supplementary Figure S1E.