Notably, as concluded in Figure 4A,C–F, patients in cluster B presented a lower proliferation rate, leukocyte score, activated CD4+ cell, activated CD8+ T cell, ImmuneScore, ESTIMATEScore, and M0 macrophage level, but had the highest Th17 cell and M2 macrophage levels, whereas patients in both clusters A and C had higher numbers in these indices, and higher tumor purity and non-silent mutations per Mb. This evidence concerns the gene CD4 and neoplasm.