We observed that five genes (HAGLR, ADAMTS9-AS2, TP73-AS1, LINC00261, and LINC00312) were downregulated in tumor vs. normal lung tissue (NSCLC, LUAD, LUSC); however, the expression was lifted in LUAD tumors in comparison to LUSC tumors. The gene discussed is HAGLR; the disease is non-small cell lung carcinoma.