To provide novel insight to precision diagnosis, we evaluated the expression of 14 lncRNAs (HAGLR, ADAMTS9-AS2, LINC00261, MCM3AP-AS1, TP53TG1, C14orf132, LINC00968, LINC00312, TP73-AS1, LOC344887, LINC00673, SOX2-OT, AFAP1-AS1, and LOC730101) in the early stages of non-small-cell lung cancer (NSCLC). Here, SOX2 is linked to non-small cell lung carcinoma.