We identified a set of 11 lncRNAs (HAGLR, ADAMTS9-AS2, LINC00261, MCM3AP-AS1, TP53TG1, C14orf132, LINC00968, LINC00312, TP73-AS1, LOC344887, and LINC00673) dysregulated in NSCLC tumors compared with normal adjacent lung tissues, as well as a panel of 10 lncRNAs (HAGLR, ADAMTS9-AS2, LINC00261, LINC00673, MCM3AP-AS1, LINC00312, TP73-AS1, AFAP1-AS1, LOC344887, and SOX2-OT) differentially expressed between LUAD tumor and LUSC tumor. This evidence concerns the gene AFAP1 and neoplasm.