In addition, myricetin inhibits the proliferation of intestinal polyps in APCMin/+ mice by modulating the localization of β-catenin in intestinal adenomatous cells and negatively regulates the expression of PCNA and the Wnt-target gene cyclin D1, reducing the number of intestinal polyps, besides promoting apoptosis by regulating pro-apoptotic proteins and inflammatory cytokines [108]. The gene discussed is CCND1; the disease is intestinal polyp.