The studied population was composed of 369 men (83.1%) and 75 women (16.9%), with a median age at the first cancer event of 46 years and a median age at the SPC event of 51 years; 47.8% were MSM, 16.0% were coinfected with HCV, 9.1% were coinfected with HBV and 76.9% had a nadir CD4 count <200/mm3 (Table 1). This evidence concerns the gene CD4 and cancer.