Approval was based on results from an international, non-randomized, open-label, multicohort EXCLAIM clinical trial (NCT02716116), which evaluated mobocertinib efficacy in a cohort of 114 NSCLC patients carrying EGFR Ex20ins mutations that have progressed on or after platinum-based chemotherapy [76,77,78]. Here, EGFR is linked to non-small cell lung carcinoma.