TP53 and lung cancer: Exosome-dependent immune surveillance at the metastatic niche requires p53 acetylation at K372 and K373 [94], and the activated miR193a/S100A6 axis suppresses the migration and proliferation of lung cancer cells via promoting p53 acetylation at K373 [95], where p53 is a well-known gatekeeper of genome integrity [96].