SERPINB3 and neoplasm: For the other tumor markers, the OS of the elevated CYFRA and SCC antigen level group was significantly shorter than that of the normal CYFRA and SCC antigen level group (CYFRA level: median, 25.7 vs. 42.7 months; log-rank test p = 0.047; HR, 1.52; 95% CI, 1.01–2.33; SCC antigen level: median, 21.1 vs. 33.9 months; log-rank test p = 0.018; HR, 1.79; 95% CI, 1.08–2.87) (Figure 3a,b); however, the PFS did not significantly differ between them.