CD163 and cancer: Therefore, a combined CD163+ TAM marker was defined with three risk categories: (1) low number of communicating CD163+ TAMs and high median cancer-to-CD163+ NND; (2) low number of communicating CD163+ TAMs and low median cancer-to-CD163+ NND; (3) high number of communicating CD163+ TAMs and any median cancer-to-CD163+ NND.