AKT1 and glioblastoma: When classifying the 12 GBM cell lines used in this study by their p-Ser 473 Akt status (Supplementary Table S1, High or Low), and comparing this with their IC50 values (Figure 1A), a correlation (p = 0.03) between high sensitivity for ATX-101 and high p-Ser 473 Akt status was detected (Supplementary Figure S1C).