STAT3 and adenoma: Indeed, the restriction of the Stat3 signaling in Gp130F/F;Stat3+/− mice yielded similar miR-21 expression levels in the glandular antrum to those observed in the non-adenomatous antrum tissue of wild-type mice (Figure 1A,B), and the expression remained significantly lower than that in the unaffected glandular antrum and the adenomas of Gp130F/F mice.