Finally, in order to better characterize the autophagy process, and to preliminarily investigate in which cell population(s) the autophagic process could be affected, we performed a flow cytometric analysis, considering the autophagic vacuoles’ accumulation rate in CD14− and CD14+ cells—PBLs and monocytes, respectively—and in total PBMCs of SLE patients. The gene discussed is CD14; the disease is systemic lupus erythematosus.