AKT1 and glioblastoma: The ability of serotonin in influencing the MAPK and AKT signal transduction pathways [70], as well as the recently characterized involvement of neuromediators and their receptors in GBM genesis, growth and aggressiveness [64,65,66], provide a strong incentive for considering the use of antipsychotic drugs to counteract GBM growth to ameliorate patient prognosis.