Hence, variations in the amount of S100B could reflect the effect of antipsychotics on neuroinflammation and, because this factor decreases in murine gliomatous models when treated with antipsychotics [110], it can be speculated that antipsychotics should possess anti-inflammatory properties in GBM patients by acting on S100B downregulation. The gene discussed is S100B; the disease is glioblastoma.