Moreover, the restoration of LCN2 expression by adenoviral infection already at a low infection rate was able to enhance IL-1β expression, while the reporter virus Ad5-CMV-GFP directing expression of GFP also under transcriptional control of the CMV promoter failed to impact IL-1β expression in LCN2-KO#1 cells (Figure 5F). This evidence concerns the gene IL1B and infection.