Notably, overexpression of hnRNP K in cells expressing expanded AUUCU RNA repeats has been demonstrated to rescue them from apoptosis, showing that the spliced expanded AUUCU RNA repeat triggers neuronal death in SCA10 through loss-of-function of hnRNP K. In interrupted alleles, the inserted pentanucleotide motifs present in affected individuals with epileptic seizures likely recruit additional RBPs relevant for phase separation of condensates with a function in gene regulation of genes associated with epilepsy. Here, HNRNPK is linked to epilepsy.