The top proteins were also enriched in PD-causing genes (three genes out of six, FET p-value 8.1 × 10−4) and included leucine-rich repeat kinase 2 (LRRK2), Parkin RBR E3 ubiquitin protein ligase (PRKN), and PTEN-induced putative kinase 1 (PINK1). This evidence concerns the gene UBE2E3 and Parkinson disease.