This is the case with several hematological malignancies, including B-cell acute lymphoblastic leukemia (B-ALL), where it was shown that STAT5 highly binds SE, notably regulating MYC and BCL2L1, thought to be a defining feature of B-ALL, by inducing B-cell transformation [62]. This evidence concerns the gene BCL2L1 and precursor B-cell acute lymphoblastic leukemia.