In multiple myeloma (MM), the MYC oncogene is frequently involved in chromosomal translocations [59], often repositioning it near genes associated with SE, such as immunoglobulin genes (e.g., IgH, IgK, IgL), FOXO3, PRDM1, and others, leading to its overexpression. Here, MYC is linked to Miyoshi myopathy.