Intraventricular hemorrhage in premature pediatric patients, as well as disorders of cerebrospinal fluid (CSF) circulation in adults, were associated with elevated levels of SP-G in the CNS, which, in combination with its amphiphilic properties, suggests the possibility of SP-G as being an important modulator of CSF homeostasis [11,12].Thus, SP-C and SP-G apparently share common features in this regard. This evidence concerns the gene SFTA2 and Intraventricular hemorrhage.