Hence, many studies showed that cutaneous manifestations of COVID-19, such as chilblain-like lesions and anosmia, are associated with good prognosis, reporting lower D-dimer and CRP levels, as well as lower ICU admission and mortality rates in patients with cutaneous manifestations of COVID-19, such as chilblain-like lesions and anosmia. This evidence concerns the gene CRP and Kallmann syndrome.