Finally, in the context of renal fibrosis caused by the loss of HNF-1β [61], HNF-1β deficient renal epithelial cells mIMCD3 showed upregulated mesenchymal traits relative to wild-type cells, as again captured by the KS, 76GS, and MLR scores (Figure 2J; GSE97770) (Table S2). This evidence concerns the gene HNF1B and renal fibrosis.