Indeed, the role of platelet-activating factor (PAF) was suggested in the pathogenesis of COVID-19 and a healthy diet containing PAF inhibitors, such as vitamin A, vitamin C, vitamin E, vitamin D, selenium, omega-3 fatty acids and minerals, may target both inflammation and thrombosis and prevent the deleterious effects of COVID-19 [44]. The gene discussed is PCLAF; the disease is COVID-19.