RIN2 and esophageal cancer: Supplementary Table S1 presents the gene symbol, p-values, probeID, and mean difference of methylation levels in high- and low-risk groups. Some identified genes include RIN2 (Figure 3D), which was previously suggested as a methylation biomarker for early stage of esophageal cancer [43], and MGC29506 (Figure 3C), which was previously suggested as a biomarker for gastric [44] and testicular cancers [23].