Similar patterns of mRNA expression were also observed for TNF-α, IL-1β, IL-8 and CXCL-10 (IP-10) cell models following ZIKV infection; however, with a much higher level of IP-10 expression observed in the ZIKV-susceptible HASTR/ci35 cells compared with the ZIKV-resistant CCF-STTG1 cells. The gene discussed is IL1B; the disease is Zika virus infectious disease.