IFNG and Zika virus infectious disease: Our data demonstrate limited upregulation of IFN-γ expression in both cell types following ZIKV infection in comparison with the levels of both type I and III IFNs; however, the more ZIKV-susceptible HASTR/ci35 astrocyte cells did demonstrate a peak of mRNA expression for type II IFN at the later timepoints (Figure 3C), coinciding with maximal virus infection.