The effects of HCMV infection in human immortalized extravillous cytotrophoblasts (HIPEC) were also analyzed, identifying 15-hydroxyeicosatetraenoic acid (15-HETE) and 13-hydroxyoctadecadienoic acid (13-HODE) as predominant PPARγ agonists secreted after HCMV infection [94]. The gene discussed is PPARG; the disease is cytomegalovirus infection.