Although the mechanisms responsible for exogenous FABP4 eliciting proliferation and migration of hepatocellular carcinoma cells have not been specifically explored, studies performed in breast cancer cells [127] and prostate cancer cells [128] suggest that exogenous FABP4 may regulate these processes through a mechanism involving membrane binding and internalization, and through the activation of cellular signaling pathways such as Akt/phosphatidylinositol 3 kinase (PI3K) and extracellular regulated kinase 1/2 (ERK1/2), among others. The gene discussed is FABP4; the disease is breast carcinoma.