Although a FABP4 threshold level should be defined for each pathological condition, it is worth noting that it is strongly associated with adiposity [105,106] and with a wide range of metabolic diseases, including endothelial dysfunction [107], metabolic syndrome [83,108], and type 2 diabetes [109], as well as cardiovascular diseases (for review see [110]). This evidence concerns the gene FABP4 and cardiovascular disorder.