Tetrahydrocurcumin, a naturally occurring curcuminoid and a metabolite of curcumin showing properties as an anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, and neuroprotective agent, reduced oleic acid-induced lipid accumulation in human hepatocellular carcinoma cells through several mechanisms, including the attenuation of lipogenesis by reducing the protein levels of FABP4, among other lipogenic proteins [136]. Here, FABP4 is linked to hepatocellular carcinoma.