It is worth noting that, while the expression of miR-122 and -128-3p was significantly increased in NAFL and NASH compared with control subjects (Figure 4), the proportion of these miRNAs in ASGR1+ EV still accounted for <30% of global EV expression and <2.5% of total cfRNA expression for each miRNA. This evidence concerns the gene ASGR1 and non-alcoholic fatty liver.