NEFL and Alzheimer disease: In the CN group (CN Aβ- vs. preclinical AD), the ∆z-scores varied in the order of CSF Aβ1–42 concentrations, Aβ-PET SUVR score, CSF NFL/Aβ1–42, CSF NFL concentrations, plasma NFL/Aβ1–42, plasma Aβ1–42 concentrations, CSF t-Tau concentrations, plasma NFL concentrations, CSF p-Tau181 concentrations, and hippocampal volume/ICV (Figure 3b).