NEFL and Alzheimer disease: The AUC values distinguishing participants with prodromal AD from CN Aβ- participants were 0.696 for plasma NFL concentrations (cut-off value > 19.0) and 0.748 for plasma Aβ1–42 concentrations (cut-off value < 9.3), whereas the AUC value for plasma NFL/Aβ1–42 increased to 0.865 (cut-off value > 2.05).