APOA1 and triple-A syndrome: A similar MS-based proteomic approach for the identification of plasma biomarkers for AAA was used by Burillo et al. [104], and this study found that apolipoprotein A1 (ApoA1) was negatively correlated with AAA size and thrombus volume, but positively correlated with HDL-Cholesterol levels in plasma and the authors claimed that targeting HDL functionality may halt AAA development.