In the most recent evaluation by an expert consensus, only three of these genes were considered to have adequate evidence to be classified as definitive for typical LQTS (KCNQ1, KCNH2, SCN5A) and four genes for LQTS with atypical features (CALM1, CALM2, CALM3, TRDN). The gene discussed is CALM3; the disease is familial long QT syndrome.