According to the recent evaluation by Adler et al., there is insufficient evidence to classify 10 of the 17 LQTS-related genes (CACNA1C, AKAP9, ANK2, CAV3, KCNE1, KCNE2, KCNJ2, KCNJ5, SCN4 and SNTA1) as LQTS-causing genes [31983240]. Here, CACNA1C is linked to familial long QT syndrome.