TNF and inflammatory bowel disease: The classical IBD treatment contains anti-inflammatory drugs (e.g., 5-aminosalicylic acid, glucocorticosteroids), immunosuppressive agents (e.g., azathioprine, 6-mercaptopurine), and anti-tumor necrosis factor (TNF)-α monoclonal antibodies (e.g., infliximab, adalimumab) [36,37,38].