In contrast, the COX5B level (p = 0.002), gender (p = 0.021), age (p = 0.003), height (p = 0.007), tumor differentiation status (p < 0.001), local invasion grade (p = 0.012), tumor size (p = 0.014), circulating CEA level (p < 0.001), adjuvant chemotherapy received (p = 0.002), OCR T/N ratio (p < 0.001), and ECAR T/N ratio (p = 0.007) were associated with DFS. This evidence concerns the gene COX5B and neoplasm.