COX5B has also been implicated as a predictor of clinical outcomes in the various cancer types, including HCC, breast cancer, glioma, gastric cancer, head and neck squamous cell carcinoma (HNSCC), and clear cell renal cell carcinoma (ccRCC) [24,29,30,31,32]. The gene discussed is COX5B; the disease is nonpapillary renal cell carcinoma.