CD8A and metabolic dysfunction-associated steatotic liver disease: In addition, HLA-DR+CD8+ T cells were significantly increased in DILI patients (12.6 ± 2.6) compared to NAFLD patients without significant liver fibrosis (F ≤ 1) (6.9 ± 1.1, p = 0.045) and healthy controls (5.0 ± 0.5, p < 0.001) (Figure 4).