HbA1c ≤ 9%T2DM: 9 (35%) in liraglutide group;Other parameters in liraglutide group:Glucose: 6.0 ± 1.7 mmol/L;Insulin: 166 ± 80 pmol/LHOMA-IR:6.7 ± 4.7 U. The gene discussed is INS; the disease is type 2 diabetes mellitus.