COXFA4 and Sepsis: However, another study utilizing H9C2 cells subjected to in vitro sepsis experimental challenge concluded that miR-210 overexpression augmented apoptotic cell death by directly binding to the 3′ UTR of the NDUFA4 (NADH-ubiquinone oxidoreductase MLRQ subunit) mRNA transcript, leading to mitochondrial dysfunction [141].