Median leptin level in plasma was significantly (p < 0.001) higher at ICU admission in COVID-19 patients (18.3 ng × mL−1; IQR (Q3–Q1) = 30.4), compared to healthy controls (7.8 ng × mL−1; IQR (Q3–Q1) = 6.4), (Figure 1a). The gene discussed is LEP; the disease is COVID-19.